Name

XIE Deyu

Gender

Male

Date of birth

September,1965

Titles

Professor, Ph.D.

Position/Group job

（1）Conference Chair, the 53rd annual meeting of Phytochemistry Society of North America, Aug. 9-13, 2014, McKimmon Center, Raleigh, NC. This was the first time that the annual meeting of the PSNA was held in North Carolina. More than 150 members attended this annual conference.

（2）REVIEW SERVICES FOR INTERNATIONAL RECOGNIZED JOURNALS

Peer-review for Journals:

Research direction

Plant Metabolomics, Metabolic Biology of Plant Flavonoids and Terpenes, and Metabolomics-Based Genetics, Biotechnology of Medicinal Plants

Recruiting doctoral subjects

Prataculture Science and Technology

Contact Email

dxie@ncsu.edu

Experience of Study abroad

• Postdoctoral Fellow, Division of Plant Biology, The Samuel Roberts Noble Foundation, Jan. 2001-Aug. 2005. Research Program: Functional Genomics, Metabolomics and Condensed Tannins Biosynthesis.

• Postdoctoral Fellow, Institute of Molecular Agrobiology, The National University of Singapore, April 1999-Jan.2001. Research Program: Acacia mangium biotechnology.

• Visiting Scientist, Institute of Molecular Agrobiology, The National University of Singapore, July 1997- April 1, 1999. Research Program: Acacia mangium Biotechnology.

Science &Teaching

Research

Projects

1. Total external funding (from government and companies, shown in Radar): $11,185,507

2. Total internal funding: $333,520

3. Total gift funding: $206,086

Papers and Works

Corey D. Broeckling, Ke-Gang Li and De-Yu Xie (Correspondent author) 2011 Comparative metabolomics of transgenic tobacco (Nicotiana tabacum Var. Xanthi) reveals differential effects of engineered complete and incomplete flavonoid pathways on the metabolome. In Transgenic Plants, 379-396。

Major papers:

Proanthocyanidins–a final frontier in flavonoid research

RA Dixon, DY Xie, SB Sharma New phytologist 165 (1), 9-28

TAA1-mediated auxin biosynthesis is essential for hormone crosstalk and plant development AN Stepanova, J Robertson-Hoyt, J Yun, LM Benavente, DY Xie, ...

Cell 133 (1), 177-191

Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis

DY Xie, SB Sharma, NL Paiva, D Ferreira, RA Dixon

Science 299 (5605), 396-399

Proanthocyanidin biosynthesis–still more questions than answers?

DY Xie, RA Dixon

Phytochemistry 66 (18), 2127-2144

Metabolic engineering of proanthocyanidins through co‐expression of anthocyanidin reductase and the PAP1 MYB transcription factor

DY Xie, SB Sharma, E Wright, ZY Wang, RA Dixon

The Plant Journal 45 (6), 895-907

A small-molecule screen identifies L-kynurenine as a competitive inhibitor of TAA1/TAR activity in ethylene-directed auxin biosynthesis and root growth in Arabidopsis

W He, J Brumos, H Li, Y Ji, M Ke, X Gong, Q Zeng, W Li, X Zhang, F An, ...

The Plant Cell 23 (11), 3944-3960

Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana

DY Xie, SB Sharma, RA Dixon

Archives of Biochemistry and Biophysics 422 (1), 91-102

Molecular and biochemical analysis of two cDNA clones encoding dihydroflavonol-4-reductase from Medicago truncatula

DY Xie, LA Jackson, JD Cooper, D Ferreira, NL Paiva

Plant physiology 134 (3), 979-994

In vitro regeneration of Acacia mangium via organogenesis

D Xie, Y Hong

Plant cell, tissue and organ culture 66 (3), 167-173

Biosynthesis and metabolic engineering of anthocyanins in Arabidopsis thaliana

MZ Shi, DY Xie

Recent patents on biotechnology 8 (1), 47-60

Regeneration of Acacia mangium through somatic embryogenesis

DY Xie, Y Hong

Plant cell reports 20 (1), 34-40

Agrobacterium-mediated genetic transformation of Acacia mangium

D Xie, Y Hong

Plant Cell Reports 20 (10), 917-922

Features of anthocyanin biosynthesis in pap1-D and wild-type Arabidopsis thaliana plants grown in different light intensity and culture media conditions

MZ Shi, DY Xie

Planta 231 (6), 1385-1400

Development of tobacco callus cultures over expressing Arabidopsis PAP1/MYB75 transcription factor and characterization of anthocyanin biosynthesis

LL Zhou, HN Zeng, MZ Shi, DY Xie

Planta 229 (1), 37

Regulation of anthocyanin biosynthesis by nitrogen in TTG1–GL3/TT8–PAP1-programmed red cells of Arabidopsis thaliana

LL Zhou, MZ Shi, DY Xie

Planta 236 (3), 825-837

A photorespiratory bypass increases plant growth and seed yield in biofuel crop Camelina sativa

J Dalal, H Lopez, NB Vasani, Z Hu, JE Swift, R Yalamanchili, M Dvora, ...

Biotechnology for biofuels 8 (1), 175

Isolation and production of artemisinin and stigmasterol in hairy root cultures of Artemisia annua

D Xie, L Wang, H Ye, G Li

Plant cell, tissue and organ culture 63 (2), 161-166

Selection of hairy root clones of Artemisia annua L. for artemisinin production

D Xie, Z Zou, H Ye, G Li, Z Guo

Israel journal of plant sciences 49 (2), 129-134

A genome-wide scenario of terpene pathways in self-pollinated Artemisia annua

DM Ma, Z Wang, L Wang, F Alejos-Gonzales, MA Sun, DY Xie

Molecular plant 8 (11), 1580-1598

Regulation of anthocyanin biosynthesis in Arabidopsis thaliana red pap1-D cells metabolically programmed by auxins

Z Liu, MZ Shi, DY Xie

Planta 239 (4), 765-781

Engineering of red cells of Arabidopsis thaliana and comparative genome-wide gene expression analysis of red cells versus wild-type cells

MZ Shi, DY Xie

Planta 233 (4), 787-805

Evolution of bract development and B‐class MADS box gene expression in petaloid bracts of Cornus s. l.(Cornaceae)

CM Feng, X Liu, Y Yu, D Xie, RG Franks, QYJ Xiang

New Phytologist 196 (2), 631-643

Shoot regeneration of dwarf dogwood (Cornus canadensis L.) and morphological characterization of the regenerated plants

CM Feng, R Qu, LL Zhou, DY Xie, QYJ Xiang

Plant Cell, Tissue and Organ Culture (PCTOC) 97 (1), 27-37

An integrated approach to demonstrating the ANR pathway of proanthocyanidin biosynthesis in plants

QZ Peng, Y Zhu, Z Liu, C Du, KG Li, DY Xie

Planta 236 (3), 901-918

Characterization of development and artemisinin biosynthesis in self-pollinated Artemisia annua plants

F Alejos-Gonzalez, G Qu, LL Zhou, CH Saravitz, JL Shurtleff, DY Xie

Planta 234 (4), 685-697

Functional characterization of tea (Camellia sinensis) MYB4a transcription factor using an integrative approach

M Li, Y Li, L Guo, N Gong, Y Pang, W Jiang, Y Liu, X Jiang, L Zhao, ...

Frontiers in plant science 8, 943

Artemisinin biosynthesis in Artemisia annua and metabolic engineering: questions, challenges, and perspectives

DY Xie, DM Ma, R Judd, AL Jones

Phytochemistry reviews 15 (6), 1093-1114

Enhanced diversity and aflatoxigenicity in interspecific hybrids of Aspergillus flavus and Aspergillus parasiticus

RA Olarte, CJ Worthington, BW Horn, GG Moore, R Singh, JT Monacell, ...

Molecular ecology 24 (8), 1889-1909

Salt stress induces differential regulation of the phenylpropanoid pathway in Olea europaea cultivars Frantoio (salt-tolerant) and Leccino (salt-sensitive)

L Rossi, M Borghi, A Francini, X Lin, DY Xie, L Sebastiani

Journal of plant physiology 204, 8-15

Tissue-specific production of limonene in Camelina sativa with the Arabidopsis promoters of genes BANYULS and FRUITFULL

M Borghi, DY Xie

Planta 243 (2), 549-561

Volatile compounds from leaf extracts of Juniperus excelsa growing in Syria via gas chromatography mass spectrometry

K Almaarri, L Alamir, Y Junaid, DY Xie

Analytical Methods 2 (6), 673-677

Functional characterization of an anthocyanidin reductase gene from the fibers of upland cotton (Gossypium hirsutum)

Y Zhu, H Wang, Q Peng, Y Tang, G Xia, J Wu, DY Xie

Planta 241 (5), 1075-1089

Overexpression and suppression of Artemisia annua 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 gene (AaHDR1) differentially regulate artemisinin and terpenoid biosynthesis

D Ma, G Li, Y Zhu, DY Xie

Frontiers in plant science 8, 77

Molecular cloning and functional characterization of the anthocyanidin reductase gene from Vitis bellula

Y Zhu, QZ Peng, KG Li, DY Xie

Planta 240 (2), 381-398

Plant regeneration and genetic transformation of C. canadensis: a non-model plant appropriate for investigation of flower development in Cornus (Cornaceae)

X Liu, CM Feng, R Franks, R Qu, DY Xie, QYJ Xiang

Plant cell reports 32 (1), 77-87

Overexpression of a synthetic insect–plant geranyl pyrophosphate synthase gene in Camelina sativa alters plant growth and terpene biosynthesis

J Xi, L Rossi, X Lin, DY Xie

Planta 244 (1), 215-230

Efficient somatic embryogenesis and organogenesis of self-pollination Artemisia annua progeny and artemisinin formation in regenerated plants

F Alejos-Gonzalez, K Perkins, MI Winston, DY Xie

American Journal of Plant Sciences 4 (11), 2206

Integration of GC-MS based non-targeted metabolic profiling with headspace solid phase microextraction enhances the understanding of volatile differentiation in tobacco leaves …

DM Ma, SVS Gandra, N Sharma, DY Xie

American Journal of Plant Sciences 3 (12), 1759

Genetic manipulation of condensed tannins

RA Dixon, NL Paiva, D Xie, S Sharma

US Patent 7,622,638

Metabolic engineering of anthocyanins in dark tobacco varieties

X He, Y Li, D Lawson, DY Xie

Physiologia plantarum 159 (1), 2-12

Analysis of two TFL1 homologs of dogwood species (Cornus L.) indicates functional conservation in control of transition to flowering

X Liu, J Zhang, A Abuahmad, RG Franks, DY Xie, QY Xiang

Planta 243 (5), 1129-1141

Characterization of flavan-3-ols and expression of MYB and late pathway genes involved in proanthocyanidin biosynthesis in foliage of Vitis bellula

Y Zhu, QZ Peng, C Du, KG Li, DY Xie

Metabolites 3 (1), 185-203

Overexpression of a type‐I isopentenyl pyrophosphate isomerase of Artemisia annua in the cytosol leads to high arteannuin B production and artemisinin increase

D Ma, G Li, F Alejos‐Gonzalez, Y Zhu, Z Xue, A Wang, H Zhang, X Li, ...

The Plant Journal 91 (3), 466-479

Metabolic characterization of the anthocyanidin reductase pathway involved in the biosynthesis of flavan-3-ols in Elite Shuchazao tea (Camellia sinensis) cultivar in the field

L Zhao, XL Jiang, YM Qian, PQ Wang, DY Xie, LP Gao, T Xia

Molecules 22 (12), 2241

In vitro direct organogenesis and micropropagation of Artemisia annua

K Almaarri, Y Xie

J. Biotechnologie Vegetale 26, 327-337

Studies on the karyotype of Artemisia annua

DY Xie, N Kang, Guo-zhen L

Chinese Bulletin of Botany 12 (Supplementary), 71-72

Artemisia annua, artemisinin, and the Nobel Prize: beauty of natural products and educational significance

DY Xie

Science Bulletin 61 (1), 42-44

Differentiation of programmed Arabidopsis cells

DY Xie, MZ Shi

Bioengineered 3 (1), 54-59

Overexpression of Populus× canescens isoprene synthase gene in Camelina sativa leads to alterations in its growth and metabolism

L Rossi, M Borghi, J Yang, DY Xie

Journal of plant physiology 215, 122-131

Regeneration and genetic transformation of Acacia mangium

D Xie, Y Hong

US Patent 6,846,971

The Progress of Artemisia annua research–the application of biotechnology and prospects

DY Xie, H Ye, G Li

Chinese Bulletin of Botany 12 (4), 28-31

Artemisia annua L. Transformation with different Agrobacterium rhizogenesis and large scale culture of hairy roots for Artemisinin (Qinghaosu) production

D Xie, H Ye, G Li, Z Guo

4th Asia-Pacific Conference on Agricultural Biotechnology-Darwin, 134-136

Comparative metabolomics of transgenic tobacco plants (Nicotiana tabacum var. Xanthi) reveals differential effects of engineered complete and incomplete flavonoid pathways on …

CD Broeckling, KG Li, DY Xie

Transgenic Plants-Advances and Limitations

Molecular cloning and functional characterization of a dihydroflavonol 4-Reductase from Vitis bellula

Y Zhu, Q Peng, K Li, DY Xie

Molecules 23 (4), 861

Cloning and characterization of a monoterpene synthase gene from flowers of Camelina sativa

M Borghi, DY Xie

Planta 247 (2), 443-457

Overexpression of Artemisia annua cinnamyl alcohol dehydrogenase increases lignin and coumarin and reduces artemisinin and other sesquiterpenes

D Ma, C Chu, F Alejos-Gonzalez, H Wang, J Yang, RS Judd, D XIE

Frontiers in plant science 9, 828

Characterization of transgenic Camelina plants emitting isoprene

L ROSSI, M BORGHI, D XIE

proceedings of the 53rd annual meeting of the phytochemical society of North …

Artemisinin biosynthesis in non-glandular trichome cells of Artemisia annua

R Judd, MC Bagley, M Li, Y Zhu, C Lei, S Yuzuak, M Ekelöf, G Pu, X Zhao, ...

Molecular Plant

Functional characterization of Terminal Flower1 homolog in Cornus canadensis by genetic transformation

X Liu, J Zhang, D Xie, RG Franks, QYJ Xiang

Plant cell reports, 1-11

Evaluation of Digital Image Recognition Methods for Mass Spectrometry Imaging Data Analysis

M Ekelöf, KP Garrard, R Judd, EP Rosen, DY Xie, ADM Kashuba, ...

Journal of The American Society for Mass Spectrometry 29 (12), 2467-2470

HPLC-qTOF-MS/MS-Based Profiling of Flavan-3-ols and Dimeric Proanthocyanidins in Berries of Two Muscadine Grape Hybrids FLH 13-11 and FLH 17-66

S Yuzuak, J Ballington, DY Xie

Metabolites 8 (4), 57

Non-plastidial expression of a synthetic insect geranyl pyrophosphate synthase effectively increases tobacco plant biomass

G Li, J Xi, X Ji, MZ Li, DY Xie

Journal of plant physiology 221, 144-155

Correction to: Cloning and characterization of a monoterpene synthase gene from flowers of Camelina sativa

M Borghi, DY Xie

Planta 247 (1), 287-288

Suspension Culture of Programmed Red vs. Wild-type Cells of Tobacco.

S Yuzuak, DY Xie

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 53, S51-S51

Compartmentalized Overexpression of a Synthetic Geranyl Pyrophosphate Synthase and Its Regulation on Plant Growth and Metabolism.

G Li, X Ji, S Swantko, DY Xie

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 53, S54-S55

Regulation of Anthocyanin Biosynthesis in the WD40-bHLH-MYB Complex-Programmed Arabidopsis Cells

DY Xie

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 53, S13-S13

Red and White PAP1-controlled Arabidopsis Cells Are Dependent Upon TT8.

Y Zhu, DY Xie

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 53, S51-S51

Ontogenetic characterization of sporangium and spore of Huperzia serrata: an anti-aging disease fern

H Long, J Li, YY Li, DY Xie, QZ Peng, L Li

Botanical studies 57 (1), 36

Metabolic Network Based Regulation of Artemisinin Biosynthesis for Anti-malarial Medicine.

DY Xie

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 52, S24-S24

Mechanisms of Metabolic Programming Toward Anthocyanin Biosynthesis in Cultured Red Arabidopsis Cells

DY Xie, MZ Shi, Z Liu

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT 49 (4), 484-485

Jet Fuel from Camelina Sativa: Engineering Plant Primary Metabolism.

H Sederoff, A Grunden, R Qu, D Xie

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 49, S28-S28

PROGRAMMING AND REPROGRAMMING OF GENE EXPRESSION: MECHANISMS OF CELLULAR SPECIFIC METABOLISMS?

DY Xie, MZ Shi

PHARMACEUTICAL BIOLOGY 50 (11), 1356-1356

Special Issue on Metabolic Plant Biology

DY Xie, A Melis

Planta 236 (3), 763-764

SELF-POLLINATED ARTEMISIA ANNUA PLANTS FORM A NEW PLATFORM TO UNDERSTAND ARTEMISININ BIOSYNTHESIS

DY Xie, F Alejos-Gonzalez, G Qu

PHARMACEUTICAL BIOLOGY 50 (5), 662-662

Regeneration and genetic transformation of Acacia mangium

D Xie, Y Hong

US Patent 7,368,631

Regeneration and genetic transformation of acacia mangium

D Xie, Y Hong

US Patent App. 11/007,194

Tannins and Related Polyphenols (Part 2)

DY Xie, RA Dixon, JPJ Marais, D Ferreira, D Slade

Phytochemistry 66 (18)

Biochemical and molecular genetic approaches to proanthocyanioin biosynthesis.

RA Dixon, DY Xie, SB Sharma, F Chen, D Ferreira

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 228, U247-U247

Genetic manipulation of condensed tannins

R Dixon, N Paiva, D Xie, S Sharma

US Patent App. 10/610,351

Studies on the relation between the changes of endogenous IPA and the growth of cell of Arnebia euchroma during the culture

DY Xie, G Li, H Ye, G L

Journal of Jishou University 14 (6), 29-31

Tissue culture and chromosome analysis of Arnebia euchroma

G Li, M Qi, N Kang, D Xie, Y Ye, G Li

Chinese Bulletin of Botany 3 (1), 37-41

METABOLIC PROFILINGAND GENE EXPRESSION ANALYSES IN SALT-STRESSED OLIVE TREES (Olea europaea L.) CULTIVARS ‘LECCINO’AND ‘FRANTOIO’

L Rossi, M Borghi, A Francini, DY Xie, L Sebastiani

OLIVEBIOTEQ 2014, 155

Patent Applications

（1） Deyu Xie and Yan Hong Regeneration and Genetic Transformation of Acacia mangium. Registered on 10 January 2000. Patent No. PCT/SG00/00010

（2） Deyu Xie and Yan Hong Somatic embryogenic Regeneration of Acacia mangium. Patent No. PCT/SG00/00110

（3） Richard A. Dixon, Nancy L. Paiva, Deyu Xie and Shashi B. Sharma Genetic Manipulation of Condensed Tannins. Patent Serial No. 10/610, 351, filed on June 30, 2003. Patent No. in Australia: PCT/US2003/020481, accepted date: 05-08-2008; Patent No. in Europe: PCT/US2003/020481, accepted date: 06-08-2008